Partial Resorption and Long-Term Volume Preservation
Space for regeneration
GUIDOR calc-i-oss CRYSTAL consists of a biphasic calcium phosphate (BCP) compound formed in the ratio 60% Hydroxyapatite and 40% phase-pure ß-TCP. The material is 100% alloplastic with no elements of animal or human origin. Macropores provide space for vascularization and bone regeneration. Open micropores of GUIDOR calc-i-oss CRYSTAL allow for optimal fluid circulation.
Replaced into Bone
GUIDOR calc-i-oss CRYSTAL is biocompatible and osteoconductive. As the phase-pure ß-TCP resorbs, it is replaced by new bone which embeds itself within the remaining hydroxyapatite component creating a stable scaffold, for long-term volume preservation.
Histological Analysis
GUIDOR calc-i-oss CRYSTAL granules (brown) embedded into newly formed bone (blue) and discernible within the granule. (Ground section) 8mm defect 2 months after placement n the sheep model (1).
Reference:
1. Image courtesy Dr. Antonio Flichy, Valencia, Spain and Dr. Heiner Nagursky, University of Freiburg in Breisgau, Germany